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However, its weight loss benefits have been widely documented

Patients may experience: Persistent fatigue and weakness Breathlessness on exertion Pallor or a slightly yellowish tinge to the skin Heart palpitations Neurological symptoms are of particular clinical concern, as nerve damage caused by prolonged B12 deficiency can be irreversible if not treated promptly

161 In a placebo-controlled trial in 54 men who had undergone surgery for varicocele, men receiving melatonin had greater improvement in semen parameters, antioxidant capacity, and inhibin B levels compared with men receiving placebo after three months

The lyophilized powder should be stored at room temperature, away from direct sunlight and moisture