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Description
In acute gouty arthritis, traditional Chinese medicine formulations have been used to suppress caspase-1 activation and IL-1 production, thereby inhibiting NLRP3 inflammasome activation and pyroptosis in THP-1 cells, ultimately improving disease outcomes (Wang N
In our study, N2IC was found to be degradated in dependence on lysosome in the presence of NAC, thus we concluded that the elimination of Notch2 may require the lysosome system
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