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Moreover, it is a time-consuming procedure with a relatively low success rate, posing challenges for large-scale studies at a population level
the findings were significant: in individuals with higher exposure or body burden, sweat concentrations of these metals generally exceeded those found in blood plasma or urine, and dermal excretion could match or surpass urinary daily output
Bjelakovic et al., 2010

This immunologic set-point, in turn, influences fungal burden, the risk of acute exacerbations, and the progression of structural lung injury
