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It serves as the rate-limiting enzyme for the de novo synthesis of GSH, which is promoted by glutamate cysteine ligase (GCL) and glutathione synthetase (GSS)
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[DOI] [PubMed] [Google Scholar] Zhang X, Zhou Z, Wang D, Li A, Yin Y, Gu X, Ding F, Zhen X, Zhou J (2009) Activation of phosphatidylinositol-linked D1-like receptor modulates FGF-2 expression in astrocytes via IP3-dependent Ca2+ signaling
