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NAD + -related metabolic reprogramming and redox homeostasis in tumorigenesis Cancer cells undergo metabolic reprogramming that provides the substrates and energy for biomass generation, to sustain the stress response and continuous proliferation
Abstract Current methods of culturing human epithelial organoids from adult stem cells may not be compatible with clinical applications as they rely on xenogeneic, chemically undefined or non-standardized components such as the basement membrane extract Matrigel
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
T cell profiling reveals high CD4+ CTLA-4+ T cell frequency as dominant predictor for survival after prostate GVAX/ipilimumab treatment
