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The marginal change in TUNEL staining somewhat mirrors the changes in mitophagy markers in the females brain, suggesting the mitophagy regulation may play a critical role in cell integrity

For example, berberine specifically, downregulates hepatic FMO3 via FXR/SHP signaling and inhibits microbial CutC activity, thereby reducing both microbial TMA generation and hepatic oxidation to TMAO [47, 55, 56], while specific probiotic strainssuch as Bifidobacterium and other butyrate producerscan displace TMA-generating taxa [43]

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Seine Hauptfunktion ist es, langkettige Fettsuren in die Mitochondrien zu transportieren , wo sie oxidiert werden, um Energie in Form von ATP zu produzieren