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This is not merely additive: the MOTS-c may amplify or extend the mitochondrial biogenesis signal beyond what training alone achieves, particularly in older adults whose endogenous MOTS-c response to exercise is blunted [2]

This approach has the potential to facilitate the development of tailored treatment strategies aimed at addressing the complexities involved in enhancing reproductive outcomes for individuals diagnosed with PCOS

Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association
doi: 10.1038/s41467-021-27029-6 62 JianqinL
