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We observed reduced weight loss in Gdf15 -KO mice on day 1, although the difference diminished by day 7 (Extended Data Fig
Furthermore, delivery systems may induce cytotoxicity or interact with endogenous biomolecules, leading to aggregation and reduced efficacy (197)

[DOI] [PMC free article] [PubMed] [Google Scholar] 188.Lu Y, et al

Pyloric sphincter seems to be more affected
