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While normal wound healing progresses through controlled inflammation, proliferation, and remodeling, chronic wounds disrupted by bacterial biofilms experience prolonged inflammation, impaired angiogenesis, and delayed tissue restoration

Changes tend to be gradual, and results are usually modest

Vitamin B12 Injections In cases of severe deficiency, malabsorption, or pernicious anaemia, intramuscular B12 injections are commonly used

Neurology 90 , 777788 (2018)
