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While normal wound healing progresses through controlled inflammation, proliferation, and remodeling, chronic wounds disrupted by bacterial biofilms experience prolonged inflammation, impaired angiogenesis, and delayed tissue restoration

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Changes tend to be gradual, and results are usually modest

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Vitamin B12 Injections In cases of severe deficiency, malabsorption, or pernicious anaemia, intramuscular B12 injections are commonly used

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Neurology 90 , 777788 (2018)

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