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For low toxicity pesticides (with LD 50 values greater or equal to 100 g/bee), measuring LD 50 for honey bees is particularly problematic, and EFSA guidelines 16 contain dedicated procedures and limit tests for those cases

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In conclusion, on the basis of the above evidence, the integrity of the mucus and the correct balance between mucus production by goblet cells and mucus degradation by intestinal microbiota, are essential for the maintenance of a health state