glutathione and ototoxicity Glutathione: Master Antioxidant, Reducing Oxidative Stress, Detoxification Role of Oxidative Stress in

Large-scale phosphoproteomics using a kinase inhibitor panel To demonstrate the power and scalability of the rapid DIA-based site-specific phosphoproteomics workflow developed here, we applied it to identify phosphorylation site targets of the ten major protein kinases in the epidermal growth factor signaling pathway using a panel of 30 kinase inhibitors (Fig

Funding Self-funding PhD students, and funding from the department of biosciences for final year project students and masters students

Disrupted function of lactate transporter MCT1, but not MCT4, in Schwann cells affects the maintenance of motor end-plate innervation

Laboratory studies examine the peptides effects on: Collagen Synthesis Studies: Investigation of collagen type I and III production stimulation in fibroblasts Wound Closure Research: Analysis of re-epithelialization, contraction, and healing rate in wound models Angiogenesis Investigation: Examination of blood vessel formation and vascular network development Fibroblast Activation: Studies on fibroblast proliferation, migration, and extracellular matrix production Growth Factor Modulation: Research on TGF-, VEGF, and other growth factor expression regulation Research protocols typically employ fibroblast cultures, keratinocyte studies, endothelial cell assays, and in vivo wound healing models to characterize tissue repair effects