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Therefore, the stimulatory effects of Zn on mitogenic signaling can be the result of at least three properties: (1) its role in the hormonal regulation of cell proliferation, (2) its activating effect on protein phosphorylation, and (3) its suppressor effect on phosphatase activity, which allows the maintenance of phosphorylation signaling [36]

Liu Y, Jiang Z, Hou X, Xie X, Shi J, Shen J, et al

doi: 10.1104/pp.106.077982

Genistein affects histone modifications on dickkopf-related protein 1 (DKK1) gene in SW480 human colon cancer cell line
