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Topical peptides that do absorb tend to produce modest results because the concentration reaching the target tissue is a fraction of what was applied

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Simultaneously, there is an enhancement of the expression of heat shock proteins (e.g., HSP70 and HSP90) and antioxidant proteins (e.g., heme oxygenase (HO-1), NAD(P)H dehydrogenase (NQO-1), glutathione reductase, glutathione peroxidase 2, and glutathione S-transferase pi (GST-pi)) [18]