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Conclusion Whilst severe B12 deficiency has a clear clinical picture with characteristic haematological and/or neurological features, establishing mild or borderline deficiency can be problematic as serum levels are maintained at the expense of tissue concentrations, and therefore serum levels of B12 may be in the low normal or borderline range despite a deficiency

Injecting too quickly forces the medication into the tissue faster than it can absorb, creating a pressure sensation that some people find uncomfortable

[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Wei T., Cheng Q., Min Y.L., Olson E.N., Siegwart D.J

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