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Spirig et al., 2010) (reviewed in Bordon, 2007), whereas activation of TLR2 by its novel endogenous ligand, -(2-carboxyethyl) pyrrole, leads to an angiogenic response that is independent of VEGF (West et al., 2010)
In the case of PDT, cancer cells that survived ALA-PDT were found to have reduced mitochondrial function and metastatic potential associated with increased HDAC activity 237,238
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