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Growth hormone secretagogues: history, mechanism of action, and clinical development
Research has demonstrated that BAC exerts a concentration-dependent inhibitory effect on mitochondrial functions, specifically targeting mitochondrial complex I
doi:10.1038/nm1604
The significance of NADPH levels to cellular survival has been demonstrated by overexpression of several cytoplasmic enzymes that synthesize NADPH leading to lifespan extension in model organisms such as Drosophila melanogaster
