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Targetable BET proteins-and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma
The application of productivity adjustment may result in a net update that may be less than 0.0 for a year and may result in the separate payment amount under this subsection for an applicable device for a year being less than such separate payment amount for such device for the preceding year
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(2) molecular dynamics simulated annealing restraining FOXO4 FH (without flexible regions) harmonically to its template structure (using a non-crystallographic force constant of 10,000 kcal mol 1 2 ), with additional dihedral angle restraints from 1 H, 15 N, and 13 C chemical shifts using TALOS-N 56 , hydrogen bond restraints (region p53 residues 48-55
