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Oxidative stress has been implicated in a number of diseases which include atherosclerosis, pulmonary fibrosis, cancer, Parkinson's disease, multiple sclerosis, and aging[6]

Furthermore, oxidative stress can impede the nucleoplasmic translocation of pancreaticoduodenal homeobox factor 1 (PDX-1), impair energy metabolism, and reduce insulin production and release (Duni et al., 2019)
Zhao Q, Zhang F, Yu Z, Guo S, Liu N, Jiang Y, et al
Skimping on sleep undermines IGF-1 LR3's potential effects