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At therapeutic doses, the small amount of NAPQI produced is neutralized by conjugation with reduced glutathione (GSH), as shown in Figure 1, a crucial tripeptide that, in an NADPH-dependent reaction, helps detoxify oxidants like NAPQI

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Gene expression analysis To obtain further insight into the mechanisms of BPC-157 participation in cell signal transduction, we carried out a quantitative real-time PCR using a Signal Transduction Path-wayFinder RT2 Profiler PCR Array, which contained a set of primers for 84 key genes representative of 18 different signal transduction pathways