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In HSCs, the level of ROS affects the transition of dormant HSCs to active HSCs through Myc-mediated processes [293]

Using transcriptomic analysis, we find that activation of the p53p21 pathway down-regulates expression of many genes involved in nucleotide metabolism

In brief, GH enhances the development of small antral follicles to the gonadotrophin-dependent stages and stimulates oocyte maturation, whereas IGFs increase granulose cell proliferation, steroidogenesis and oocyte growth in most mammalian species[101]

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