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B12 is a water-soluble vitamin, and when administered under medical supervision, its a safe and effective way to improve energy and support metabolism

( Related article : Homocysteine) Tryptophan metabolism : Vitamin B6 is an important cofactor in the kynurenine pathway for tryptophan metabolism, resulting in the formation of niacin

Other reasons that may cause low vitamin B12 deficiency in the body include alcohol consumption, having Sjgren's syndrome over six times, age-related factors such as chronic atrophic gastritis, and rare genetic disorders such as Imerslund-Grsbeck syndrome, and autoimmune conditions such as lupus or type 1 diabetes are associated with an increased risk of low B12

Like with any supplementation, it is important to follow professional guidance and monitor your response to the injections