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The activity of the mitochondrial enzyme, glycine decarboxylase (GDC), is sensitive to oxidative stress (Taylor et al., 2002), and this enzyme has recently been shown to be inhibited by thiol modifications on several cysteine residues (Palmieri et al., 2010)
However, a 2025 safety review argued that BPC-157 appears to regulate angiogenesis in a context-dependent manner
2013;62 doi: 10.1136/gutjnl-2011-301346
