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The crystal structure of IRAP in complex with 44 reveals that the enzyme undergoes structural reconfiguration that allows the accommodation of bulky side chains of the inhibitor

51 Importantly, chelation of iron with DFO reduced LPO but had no effect on the injury, suggesting a non-ferroptotic mode of cell death
(Wer schon einmal versucht hat, mit einer Zerrung im Beinbizeps zu trainieren, wei, wie schlecht das funktioniert