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Flavonoids have already been shown to have both anti-inflammatory and antioxidant effects [96]

In one randomized controlled trial, the authors [82] investigated 60 patients with severe pre-eclampsia requiring termination of pregnancy and divided them into two groups: the first group received 70 mg silymarin as a single dose, and the second group received 600 mg NAC at 0, 12 and 24 h after delivery

Taken together, these results suggest regulation of GS may also be important in determining the overall GSH synthetic capacity under certain conditions and especially in non-hepatic tissues

This rivalry causes T cell exhaustion and ferroptosis, decreased memory formation and cytokine release, increased PD-1 and TIM-3 expression, and intracellular oxidative stress