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p15(INK4B) CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing

Mechanism of action: Although its exact mechanism of action is not yet fully understood, it is believed to affect neurotransmitters and neurochemical pathways in the brain that regulate sleep and stress

The cytotoxicity of hydrogen peroxide primarily occurs through its ability to generate hydroxyl radical through metal-catalyzed reactions, such as the Fenton reaction (reaction 2) In biology it seems likely that this reaction is particularly important as part of the Haber-Weiss reaction, where iron (or copper) is maintained in a reduced form by superoxide and hence capable of catalyzing the formation of the hydroxyl radical from hydrogen peroxide (134)

10.1016/j.jtherbio.2018.12.004 J Therm Biol