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These include people who have had organ transplants, and those who are on immuno-suppressive therapies

For example, these nanosheets show anticancer effects by generating ROS via FDX1-mediated Cu 2+ reduction to Cu + , enhancing chemotherapy efficacy [311, 312]

Migration distance (m) across the gap of monolayer primary lung fibroblasts ( in vitro scratch assay) from aged (24 months) C57BL/6 mice shows increased migration with rising GHK concentrations (ng/ mL) over 0-48 hours

Altogether, these results demonstrate significant bidirectional changes in productivity between adapted and non-adapted cultures and raise the possibility that changes in DNA methylation might underpin the observed phenotypic differences
