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Description
Neoplasia 12 , 254263 (2010)
10.1126/science.1219855 95 YousefiS.GoldJ
In this five-year update of the ECHELON-2 trial, the frontline treatment of patients with PTCL using A + CHP continues to provide clinically meaningful improvements in PFS and OS compared to CHOP, with a manageable safety profile, including the continued resolution or improvement of peripheral neuropathy [226]
The gene product, ALDH2, localises to the mitochondria where it catalyses the detoxification of aldehydes
