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Garcia-Estrada J, Garcia-Segura LM, Torres-Aleman I: Expression of insulin-like growth factor I by astrocytes in response to injury
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Certain pathological conditions leading to catabolic stress where intracellular glutamine levels may drop below 50% and plasma concentration below 30%, body requirement for glutamine overwhelms the capacity of body for de novo synthesis of glutamine (21), and therefore depends on dietary glutamine supplementation
