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Observed effects in human trials Reported adverse events across the IV and oral trials included headache, fatigue, dizziness, nasopharyngitis, diarrhea, flatulence, increased appetite, nausea, and back pain

These results were confirmed in vitro in CRC cell lines observing reduced proliferation, cell survival, migration and invasion

Miyazawa T, Burdeos GC, Itaya M et al (2019) Vitamin E: regulatory redox interactions

Alcohol Alcohol consumption can make it harder for the body to maintain healthy nutrient levels, including vitamin B12
