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[DOI] [PubMed] [Google Scholar] [35].Pratico D, Clark CM, Liun F, Rokach J, Lee VY, Trojanowski JQ

In another study using HT22 cells, huperzine A (HupA) + wortmannin treatment stopped the downregulation of p-mTOR, p-Akt, and p-p70s6 kinase under oxidative glutamate toxicity, leading to the conclusion that HupA abrogates oxidative glutamate toxicity in mouse hippocampal cells via the activation of the BDNF/TrkB-dependent PI3K/Akt/mTOR signaling pathway 51

10.1186/s12889-022-14636-1 Summary Keywords SARS-CoV-2, post-COVID cognitive impairment, neuroinflammation, mitochondrial dysfunction, neurodegeneration Citation Li Z, Zhang Z, Zhang Z, Wang Z and Li H (2023) Cognitive impairment after long COVID-19: current evidence and perspectives

Relying solely on food sources may limit the potential for significant increases in glutathione levels