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Method of Residual The value for k a cannot be obtained directly from the plasma-level time curve for the drug administered by oral route as we calculated the elimination rate constant (k), but it could be obtained using the method of residuals or a feathering technique, which is illustrated in the following graph: On a semilog paper, plot the relation between plasma drug concentrations versus time

[DOI] [PubMed] [Google Scholar] 14.Cocuzza MS, Tiseo BC, Srougi V, Wood GJA, Cardoso J, Esteves SC, et al