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Trends Immunol (2019) 40:112033
5, pp2784-2790 [online] Available at: Miranda, J., Lasa, A., Bustamante, M.A., Churruca, I

mTOR is a key mediator of the insulin signaling pathway and its chronic activation in diabetic hearts suppresses insulin receptor substrate blocking PI3K/Akt signaling and resulting in insulin insensitivity (Suhara et al., 2017)