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Multiplex immunofluorescence of these tumor tissues showed an increase in CD8 + T cells migrating from the stroma to the panCK+ tumor cell nests following ICT treatment, along with an increase in IFN in the tumor microenvironment (TME) and a concomitant enrichment in tumor cells expressing S100A9 and IFNGR1 (Fig

doi: 10.1016/S2213-8587(14)70225-6
Resta F, Micheli L, Laurino A, Spinelli V, Mello T, Sartiani L, et al

Mechanisms of DNA damage, repair, and mutagenesis
