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In addition, KD enhances the activity of antioxidant enzymes, including SOD, CAT, and GPx, and reduces the level of MDA, a marker of oxidative stress

Curcumin is often described as a hormetic compound because it induces an adaptive stress response: it mildly stresses cells in ways that activate Nrf2 and other transcription factors, leading to increased production of antioxidant and cytoprotective proteins (e.g., heme oxygenase-1) that precondition cells against subsequent injuries (77, 78)

The LKKTETQ region is widely used as a short synthetic representation of the T4 actin-binding domain, although full-length T4 has broader structural contacts and biological functions than a single short motif aloneincluding an N-terminal helical region (residues 116), the central actin-binding domain, and a C-terminal helical region (residues 3040)

They promote tissue repair, resolve inflammation, and clear cellular debris