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However, given the complexity of hair growth dynamics, research conducted employing hair follicle organ culture and systemic-like treatment, and the potential of pleiotropic effects of certain cannabinoids seen to date, additional research is needed, including clinical trials, to determine if phytocannabinoids like CBD can be effective topical interventions to treat hair loss or excessive hair growth conditions

57 UA exerts its influence on the renin-angiotensin system through dual mechanisms involving the stimulation of plasma renin activity and renal renin expression

Mechanical threshold depends on the kinetic of calcium release from and reuptake by sarcoplasmic reticulum, also in relation to basal cytosolic calcium concentrations

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