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It is one of many cellular antioxidant enzymes, including other GPxs, peroxiredoxins, and catalases, that reduce hydrogen peroxide [2]
Signals in an AMPKdependent manner, amplifying glucose uptake, inhibiting the folate cycle and de novo purine biosynthesis during metabolic stress, and shifting cellular metabolism toward enhanced stress resilience and efficient fuel use
doi: 10.1002/bab.2312 110
[DOI] [PubMed] [Google Scholar] 20.Harding J.J., van Heyningen R
