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By blocking NNMT activity, it increases critical cellular metabolites (SAM, NAD) that drive downstream increases in energy expenditure and metabolic health 1-4

In endothelial cells, BPC-157 activates ERK1/2 signaling, enhancing proliferation, migration, and vascular tube formation through transcription factors including c-Fos, c-Jun, and Egr-1

A meta-analysis of 12 clinical trials measuring flow-mediated vasodilation (FMD
