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Mechanistically, this compound can inhibit the NF-B pathway and NLRP3 inflammasome activation, reducing inflammatory responses, restoring gut barrier function by enhancing goblet cells and tight junction proteins (ZO-1 and occludin) and modulating intestinal microbiota diversity [566]

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RStudio and R-3.2.2 (53) ( was used for all statistical analysis, and significance was accepted at p 2 points or 1 SD in VABS-II composite scores were used to discriminate responders. Out of the 19 who completed the behavioral assessments in the CRWP group, 12 were identified as responders vs

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