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In CADASIL, the defect is attributable to the pathological accumulation of TIMP3 in the endothelial-pericyteshared basement membrane, which drives a decrease in the synthesis of PIP2 in capillary endothelial cells (Figure 21D) (229, 434, 504, 511, 512)

for instance, studies indicated that hirsutism, acne, and TAC were significantly decreased, and TAC was improved after 8 weeks of a daily intake of 200 g [138]

Future studies are still needed evaluating the safety and efficacy of BPC 157 in humans

This blend appears to present an opportunity to harness the synergistic actions of both to potentially augment natural growth hormone levels