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Signs of deficiency include: Fatigue and low energy Memory issues and brain fog Numbness or tingling in the hands and feet Mood swings or depression Pale skin and shortness of breath Supplementing Safely: Dosage and Absorption Tips While B12 is generally safe as its water-soluble (meaning excess is excreted), certain considerations can help you get the most out of your supplement: Sublingual Supplements : These are absorbed directly into the bloodstream, bypassing the digestive system, making them ideal for those with absorption issues

If you work with a Hone physician to get vitamin B12 injections, follow their instructions about where and when to administer the jabs

The schedule can change based on the persons health, how bad the deficiency is, and how well they respond to treatment

Song Q, Wang J, Griffiths A, Song Z (2021a) NNMT aggravates hepatic steatosis but alleviates liver injury in alcoholic liver disease" and "Two sides of NNMT in alcoholic and non-alcoholic fatty liver development"