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Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified

AMP-activated protein kinase-driven lipid droplet dynamics govern melanoma sensitivity to polyunsaturated fatty acid and iron-induced ferroptosis

At present, there are a large number of natural compounds-related studies registered on ClinicalTrials.gov, but most of the completed projects have not published their results, and most of the studies are in phase I/II clinical trials, with only a few studies in phase III