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Digital marketplaces including Amazon, Lazada, Shopee, and specialized beauty platforms have democratized access to niche brands previously available only through traditional retail, enabling consumers in rural and semi-urban areas to access premium formulations

The dense extracellular matrix (ECM) excessively secreted by PSC creates a physical hurdle that contributes to increased interstitial fluid pressure 10 , impaired hemoperfusion 11 , cellular hypoxia 12 , and blockage of nutrient and drug delivery 13

The short answer is were not sure

These discoveries contribute to a deeper understanding of the underlying mechanisms of these mood-stabilizing medications in the context of BD [30]
