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Kagan, V., Serbinova, E

Chem Res Toxicol 16(6):750756 Kreppel H, Bauman JW, Liu J, McKim JM Jr, Klaassen CD (1993) Induction of metallothionein by arsenicals in mice

Interestingly, smoking cessation normalizes the CYP1A2 activity, which in turn can lead to adverse drug reactions if not managed appropriately Research demonstrates that after sudden smoking cessation in heavy smokers, caffeine clearance decreased significantly, and this was accompanied by an apparent significant decrease in the half-life of CYP1A2 (van der Plas et al., 2020)

Although not yet definitively demonstrated, the CYBRD encoded protein (DCYTB) may be the ferrireductase in the plasma membrane of the hepatocyte
