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Iliceto S, Scrutinio D, Bruzzi P, et al

By contrast, urinary carnitine changes reflect early defects in proximal tubular reabsorption, supporting kidney-specific phenotyping
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Moreover, a similar level of reduction of CoQ 10 levels in 4-NB-treated T67 human glioma cells (by 50%) was demonstrated to cause higher cellular and mitochondrial oxidative stress (demonstrated by increased DCFH-DA and MitoSOX signals) as well as an elevation of nitric oxide (NO ) levels (338)
