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Description
Nuclear NAD + is generated by nuclear NMNAT1 and is largely utilized by PARPs for DNA damage response and nuclear sirtuins such as SIRT1, SIRT6 or SIRT7 for epigenetic deacetylation 82,86
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And because it doesnt raise IGF-1 levels or disrupt glucose regulation the way full HGH can, its safety profile is favorable
Plus, the symptoms of low B12 can be very subtle, or they may be confused for symptoms of other conditions
