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4.2 Ferroptosis and rheumatoid arthritis Rheumatoid arthritis (RA) is the typical autoimmune disease that primarily targets the synovial membrane of the joints, resulting in the synovium transforming into a hyperplastic and invasive tissue that destroys cartilage and bone (128)

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New members of the APT family, such as ABHD10 and ABHD17, belong to the / hydrolase superfamily, suggesting a broader depalmitoylase landscape beyond the canonical APT1 and APT2 (48)
