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Tissue damage accumulates

conceived the hypotheses, obtained funding, designed the studies, supervised P.K., analyzed and interpreted data, created tables and figures, and wrote, edited and finalized the manuscript

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recently showed that direct GPx4 overexpression in the cellular models (A549, H460 and H1299 and H23) of non-small cell lung carcinoma (NSCLC) prevented the radiation-induced lipid peroxidation and, in turn, contributed to radioresistance by blocking the ferroptosis mode of cell death [56]