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It is an intracellular metabolic-enzyme modulator, which is why its research read-outs are things like NAD+ levels and adipocyte gene expression, not how full you feel. That mechanistic distinction is the single most important thing to understand before looking at any dose number

For this reason, taking a B12 injection is much more efficient as it will be absorbed directly into the bloodstream, dramatically increasing the usable amount available to the cells in our body

Christian Medical College, Vellore India 2011