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As an example, the ratios of saturated to unsaturated WE and Chl-E, which are major lipid classes of normal human meibum, have been shown to be 1:4.6 and 4:1, respectively [5, 64]

Addisons Disease Addisons disease, also known as adrenal insufficiency or primary hypoadrenalism, is an endocrinopathy characterized by reduced glucocorticoid production due to progressive destruction of the adrenal cortex, typically caused by autoimmune disease, cancer, or infection [81]

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