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These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance

Review the tissue-specific sections above and the relevant condition guides to narrow the compound selection
Khrle J (2015) Selenium and the thyroid

Once your GP establishes the need for ongoing therapy and you complete training, they can issue a repeat prescription for hydroxocobalamin ampoules and injection supplies, which you collect from community pharmacies
